Publikacja naukowa 

Diagnostyka przewlekłego zapalenia błony śluzowej macicy u niepłodnych kobiet bezobjawowych: badanie porównawcze histologii, hodowli mikrobiologicznych, histeroskopii i mikrobiologii molekularnej

Author(s): dr Inmaculada Moreno; Iolanda Garcia, lekarz medycyny; Carlos Simon, lekarz medycyny, doktor.

Wyniki potwierdzone mikrobiomem ocenionym za pomocą sekwencjonowania nowej generacji

Chronic endometritis is a persistent inflammation of the endometrial mucosa caused by bacterial pathogens such as Enterobacteriaceae, Enterococcus, Streptococcus, Staphylococcus, Mycoplasma, and Ureaplasma. Although chronic endometritis can be asymptomatic, it is found in up to 40% of infertile patients and is responsible for repeated implantation failure and recurrent miscarriage. Diagnosis of chronic endometritis is based on hysteroscopy of the uterine cavity, endometrial biopsy with plasma cells being identified histologically, while specific treatment is determined based on microbial culture. However, not all microorganisms implicated are easily or readily culturable needing a turnaround time of up to 1 week.


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