Meet CentoCloud

Introducing our clinical decision support platform that delivers best diagnostic insights for your patients.

Request a demo  Episode 7: Decentralized Diagnostics

Introducing CentoCloud

With CentoCloud, we enable laboratories around the world to establish and run state-of-the-art genomic testing and deliver best diagnostic insights for your patients.

Our fully automated bioinformatics pipeline analyzes Next Generation Sequencing (NGS) data based on CENTOGENE’s validated testing products, annotated with data from the CENTOGENE Biodatabank.

Do you need to analyze sequencing data or require a medical reporting service for your genetic diagnostics offering? CentoCloud and our associated services provide a flexible and reliable solution to meet your requirements.

CENTOGENE Snapshot CentoCloud
  • Automated, state-of-the-Art bioinformatics pipeline
  • Phenotype-genotype unified database
  • Variant annotation, powered by advanced tools and data sources
  • Variant prioritization and classification algorithm (AI)
  • Variant filtering tool
  • 30+ publications powered by bioinformatics experts

Check-out the following episodes to discover how CentoCloud provides a flexible end-to-end solution

NEW: Episode 7

Decentralized Diagnostic Solution

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Episode 6

Medical Reporting

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Episode 5


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Episode 4

Innovative Bioinformatics

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Episode 3

Secure Solution

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Episode 2

Knowledge Transfer

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Episode 1

Our Diagnostic Portfolio

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NEW: Episode 7

CentoCloud® – Your Decentralized Diagnostic Solution

CENTOGENE provides premium quality services to ensure our customers achieve their goals & objectives in delivering the highest quality diagnostics. With CentoCloud, we enable laboratories around the world to establish and run state-of-the-art genomic testing and deliver best diagnostic insights to local patients.

Drawing on more than 15 years of rare and neurodegenerative disease diagnostic experience and streamlined processes, CentoCloud enables high-quality and accurate diagnostics like CENTOGENE offers in its own certified state-of-the-art labs. But what does this exactly look like in action? Keep reading to learn more about our decentralized diagnostic solution.

Decentralized Diagnostics
  • Unique diagnostic portfolio
  • Highest quality bioinformatics and variant annotation
  • Associated services
  • High-quality reporting

Analyze, interpret, and report genomic variants with confidence.

CENTOGENE CentoTalk – Discover a New World of Medical Diagnostics

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CentoCloud – Discover a New World of Medical Diagnostics

Nov 2, 2022 | English

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Diagnostic Portfolio

Discover our uniquely curated diagnostic portfolio with outstanding clinical coverage

The product offering combines the CENTOGENE Biodatabank, what is believed to be the world’s largest real-world data repository for rare and neurodegenerative diseases, with Twist Bioscience’s library preparation and target enrichment capabilities to deliver multiple assays for rare disease diagnosis and analysis. Whether choosing Whole Exome Sequencing, Whole Genome Sequencing, a rare disease panel, or our hereditary oncology panel, you can rest assured that you are receiving best-in-class genetic testing.

With our unique CentoCloud Portfolio of some of our best diagnostic solutions, we provide the best quality in clinical coverage and diagnostic results for NGS-Laboratories around the world.

Episode 1 – Diagnostic Portfolio

Gain access to:
  • Superior panel/assay design, which is validated and driven by CENTOGENE’s medical expertise and intellectual property in clinical diagnostics
  • Unique variant coverage based on proprietary variants from the world’s largest and most diverse rare disease patient cohorts and public databases
  • Best diagnostic reliability via end-to-end validated gene panels containing fully curated variants that comply with the highest standards of CAP/CLIA requirements
  • Comprehensive and highly sensitive custom designed panels that include copy number analysis to deliver our customers the best performance and accuracy

Knowledge Transfer

Gain the same high quality and diagnostic accuracy as CENTOGENE offers in its own certified state-of-the-art labs

With CentoCloud-associated services, you unlock access to our knowledge and technology, including over 15 years of proven processes, training & qualification, sequencing protocols, as well as validation & verification support to those just starting out with NGS operations. We understand that setting up an NGS-based sequencing laboratory is challenging, but we are here to support you every step of the way and provide premium quality & services to ensure you achieve your goals & objectives in delivering the highest quality of diagnostics.

Episode 2 – Knowledge Transfer

We provide you with:


We enable local in-house wet lab operations through support with workstation setup and validation.

Proven Workflow Blueprint

Validated and accredited workflow in accredited facility and certified labs (CLIA, CAP, ISO 15189, CMS).

Sequencing Protocols

Ready-to-use protocols created based on CENTOGENE’s more than 15 years of diagnostic experience.

Training and Qualification

Training programs at CENTOGENE’s Rostock headquarters or on-site at your laboratory.

Secure Solution

Rest assured with CENTOGENE’s certified promises

CENTOGENE has a life-long commitment to protecting the privacy of our patients’ data, which is secured and handled with the greatest level of care and in accordance with applicable regulations and laws. With our CE-marked CentoCloud bioinformatic analysis, we assure you that you are choosing a safe and secure solution for your laboratory.

Episode 3 – Secure Solution

Innovative Bioinformatics

Receive the highest quality bioinformatics and variant annotation

Thanks to the fully automated bioinformatics pipeline and AI-based genomic variant prioritization you can accelerate your time to diagnosis, without compromising on quality, in a cost-effective, flexible, and rapid manner.

Variant annotation is based on our proprietary Biodatabank, which is believed to be the world’s largest real-world data repository for rare and neurodegenerative diseases, as well as other public databases.

Episode 4 – Innovative Bioinformatics

CENTOGENE Why Choose Header Helix DNA

The CENTOGENE Biodatabank

Gain insights from the world’s largest real-world data repository for rare and neurodegenerative diseases

Our Biodatabank empowers CentoCloud through its over 650,000 analyzed cases from around the globe, including Whole Exome Sequencing and Whole Genome Sequencing data and Human Phenotype Ontology terms from over 33,000 patients.

The challenge of variant interpretation usually remains at the forefront of diagnostic challenges, in part due to the missing gene-phenotype link. To truly be able to establish a complete clinical picture of our patients we gather important, medically relevant information, including socio-demographic and clinical data. We do this in an integrated manner that allows us to comprehensively combine clinical and analytical test information for every patient, thus creating an expansive multiomic data set that supports discovering and confirming gene-disease associations. Ultimately, this results in higher diagnostic yield.

Episode 5 – Biodatabank

Medical Reporting

Receive advanced medical insights

High-quality reporting is key to building a partnership of trust. Over the past 15 years, CENTOGENE has been pioneering the path to advanced diagnostic testing – providing patients and physicians comprehensive answers they can trust. CentoCloud’s extensive medical reports contain thorough expert interpretation of clinical data and individualized medical recommendations and differential diagnostic approaches, as well as detailed interpretation of key findings along with actionable results.

With our medical report add-on, you can rest assured that you are choosing the most thorough diagnostic overview – combining up-to-date scientific knowledge, our clinical expertise, and unique insights.

Episode 6 – Medical Reporting

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Want to discover more?

With CentoCloud, you’re not “just” receiving a clinical decision support platform – you are gaining a team of experts, insights, and answers that you can trust, no matter where you are located.

Want to find out more? Request a free demo or access our CentoCloud Webinar!

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CentoCloud – Technical Sheet

Technical Specifications about sequencing platforms, library kits and data files

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