Disturbed lipid metabolism causes congenital disease

Lipid metabolism is crucially involved in embryonic development, and recent research uncovered yet another link.

Lipid metabolism is crucially involved in embryonic development, and recent research uncovered yet another link. Genetic screening revealed that inactivation of the enzyme sphingomyealinase-3 results in prenatal abnormalities, and in vitro studies defined the underlying pathophysiology. The study, to which CENTOGENE contributed significant genetic data, was published in the highly prestigious American Journal of Human Genetics.