IPSEN Sponsored Program
This program focuses on hereditary cholestatic liver diseases—conditions in which genetic defects disrupt bile formation or transport. These include both syndromic and non‑syndromic causes such as Progressive Familial Intrahepatic Cholestasis. (PFIC), Alagille syndrome (ALGS), or bile acid synthesis defects, which are often presented with persistent jaundice, abnormal liver function tests, pruritus, or relevant family history. Testing through this program enables a broad, efficient evaluation of multiple potentially relevant genes based on a single clinical indication.
Following the genetic analysis, CENTOGENE provides the treating physician with a comprehensive report detailing the patient’s test results, along with relevant findings, interpretation, and clinical considerations.
IPSEN does not receive any patient data; all testing, reporting, and clinical decision‑making take place exclusively between CENTOGENE and the treating healthcare professional. Participation in the program does not create any obligation for physicians to recommend, prescribe, purchase, or support any Ipsen product or service.
This test is intended for patients with:
Exclusions: This program does not cover patients with suspected extrahepatic causes of cholestasis (e.g., biliary atresia, choledochal cyst, large‑duct PSC) or cholestasis primarily related to parenteral nutrition.
This Program is Sponsored and Funded by
Physicians may request a CentoCard® sample collection kit via the request form on this page. All test orders must be placed by qualified healthcare professionals.
Ipsen medical employees may provide information about the program reactively in response to unsolicited inquiries.
During the patient visit, the physician:
All materials are included in the CentoCard® kit. Completed kits must be shipped directly to CENTOGENE.
Before shipping the sample:
Please ensure the email address on the CentoCard® matches the one used for your CentoPortal® account.
Prepare the sample according to the included instructions. Each kit contains a return shipping label. Attach it securely to the envelope, then schedule courier pickup using the tracking code by emailing: logistics@centogene.com.
Physicians will receive the patient’s results via CentoPortal® within 20 business days after the sample arrives at CENTOGENE. Notifications are provided when the sample is received and when results are ready. Results can be accessed under the My Orders section in the portal.
CENTOGENE performs whole‑genome sequencing (WGS), offering broad gene coverage for inherited cholestatic liver disorders. Technical details (e.g., sequencing depth, variant detection processes, reporting standards) are provided upon request and included in every medical report.
Quick guidance on navigating the CentoPortal® is available in the FAQ section.
General program information is available on this website. Genetic testing must be ordered by a qualified healthcare professional. Patients should consult their treating physician for questions regarding diagnosis, genetic testing, or disease management.
Ipsen does not access any patient data. All personal information and test results remain strictly between the treating physician and CENTOGENE.
Orders and Program Inquiries
CENTOGENE GmbH
Am Strande 7
18055 Rostock
+49 (0) 381 80 113-416
(Mo–Fr: 8 a.m.–6:30 p.m. CET)
customer.support@centogene.com
Website:
centogene.com
Online Ordering:
centoportal.com
This program is available in participating ex‑US countries. Availability, eligibility, and activation timelines may differ depending on regional regulatory and contractual requirements.
Whole‑genome sequencing (WGS) to analyze genes associated with PFIC, ALGS, bile acid synthesis defects, and other hereditary cholestatic disorders.
Yes, cascade testing of family members may be available depending on clinical relevance. Please refer to your treating physician for any questions.
No. Testing and shipment are fully funded through the sponsored program.
Follow the instructions in your kit. CENTOGENE Customer Support can assist with practical questions.
No. Only qualified physicians can order genetic testing. Please refer to your treating physician for any questions related to the program.
Via CentoPortal® within 20 business days after sample receipt.
Go to www.centoportal.com, click Sign Up, and follow the steps to create your login.
CENTOGENE Customer Support:
customer.support@centogene.com or +49 (0) 381 80 113‑416. (Mo–Fr: 8.00 a.m.–6:30 p.m.)
Please contact the CENTOGENE Customer Support at:
customer.support@centogene.com
Yes. CENTOGENE complies with data protection and quality standards. Patient information is shared only with the treating physician. The sponsoring pharmaceutical company receives only anonymized monthly summaries for statistical and billing purposes.
Disclaimer: This genetic testing program is funded by Ipsen as part of its independent medical initiatives. Ipsen’s role is limited solely to providing financial support; Ipsen has no involvement in the conduct of any genetic testing, the generation of results, or any clinical decisions arising therefrom. No patient data or test results will be collected, accessed, or processed by Ipsen. All patient information and testing outcomes remain exclusively with the relevant healthcare professionals and testing laboratories. This program is not intended to promote or support the sale or use of any pharmaceutical product or commercial offering. Healthcare professionals retain full responsibility for all clinical decisions, and participation does not create any obligation to prescribe, recommend, or use any Ipsen product.
Mon. – Fri. 7 a.m. – 6:30 p.m. CET
Sat. 8 a.m. – 12 p.m. CET
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