Defective mRNA Translation and Neurodegeneration

EIF2AK2 missense variants associated with early-onset generalized dystonia

Based on their size and inability to renew, nerve cells are highly vulnerable to defects in many cellular processes, including the translation of mRNA. A recent study involving several researchers from CENTOGENE further emphasizes the importance of proper mRNA translation for neuronal survival. These insights were published in Annals of Neurology, one of the most prestigious journals in the field.


  • Demy J S Kuipers
  • et al.