Newly suggested gene-disease associations need confirmatory follow-up by large-scale epidemiological studies; CENTOGENE actively engages in pertinent research projects. A recent example addressed the hypothetical link between ANO3 and movement disorders. Screening of >1,000 patients revealed strong support of a pathogenic role for heterozygous ANO3 missense variants in Parkinson’s disease and dystonia. The findings were published ahead of print in Parkinsonism & Related Disorders ahead of print on January 2nd.
Newly suggested gene-disease associations need confirmatory follow-up by large-scale epidemiological studies; CENTOGENE actively engages in pertinent research projects. A recent example addressed the hypothetical link between ANO3 and movement disorders. Screening of >1,000 patients revealed strong support of a pathogenic role for heterozygous ANO3 missense variants in Parkinson’s disease and dystonia. The findings were published ahead of print in Parkinsonism & Related Disorders ahead of print on January 2nd.
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