Author(s): Rolfs, Prof. Arndt, MD, Reetz, Kathrin, MD, Dogan, Imis, PhD, Binkofski, Prof. Ferdinand, MD, Schulz, Prof. Jörg B., MD, Laird, Angela R., PhD, Fox, Peter T., MD, Eickhoff, Simon B., MD
We exemplarily illustrate how to supplement specific functional information of current morphometric findings in the autosomal dominant spinocerebellar ataxia 17. Read more!
Spinocerebellar ataxia type 17 (SCA17) is a rare autosomal dominant neurodegenerative disorder characterized by progressive cerebellar ataxia but also a broad spectrum of other neuropsychiatric signs. As anatomical and structural studies have shown severe cerebellar atrophy in SCA17 and a differentiation of the human cerebellum into an anterior sensorimotor and posterior cognitive/emotional partition has been implicated, we aimed at investigating functional connectivity patterns of two cerebellar clusters of atrophy revealed by a morphometric analysis in SCA17 patients
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