Mutation database CentoMD®

CentoMD® 4.0 is transforming the future of medicine. Revealing the cause of a genetic disease has an immediate impact on a patient; using all the available information allows physicians to diagnose and treat hereditary diseases in a much more efficient, timely and targeted manner.

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  1. Mutation Database CentoMD®

Finding the missing pieces of information with CentoMD®

CentoMD® 4.0 provides not only the largest unique repository of genetic variants from a worldwide cohort of patients, but also a systematic and peer-documented combination of all identified variants with clinical data. The daily work of hundreds of thousands of physicians and researchers worldwide can be enhanced with a simple click.


CentoMD® vs. other databases


Why choose CENTOGENE?

Expert medical consultation


Advanced logistical solutions from sample sending to report administration


CentoMD® global genotype-phenotype database for rare diseases


Shortest turnaround time and fast reporting


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CentoMD® contains unique clinically relevant variant information

CentoMD® includes a significant number of unpublished relevant variants from a worldwide cohort of patients.

It is continuously updated with actual information on identified genetic variants, providing the medical community with detailed, nearly real-time analysis on the overall frequency and clinical significance of the most recently observed genetic variants and mutations.



>135,000

Analyzed cases


>3,200

Associated phenotypes


>925,000,000

Identified alleles


>4,500,000

Unique variants


Advanced genotype to phenotype and phenotype to genotype modules

Besides variant-based queries, CentoMD® 4.0 enables symptoms-based queries based on Human Phenotype Ontology (HPO), returning potential candidate genes and associated variants underlying the symptoms of interest.