Ear, Nose, & Throat
Rapid and informative postnatal testing for genetic disorders of the ear, nose, and throat allow for genetic counseling and may facilitate early interventions to significantly improve prognoses. With the ear being essential for many of our most basic functions, it is crucial to initially distinguish between genetic disorders and those due to environmental influences. Having identified genetic variants associated with ear-related diseases in over 190 different genes, our testing options can help pinpoint the exact cause of inherited deafness and related syndromes in your patients.
CentoHear includes 199 genes associated with syndromic and non-syndromic hearing loss. Hearing loss is a common condition in children, affecting 1 in 100 live births. In more than 50%, there is a genetic cause for this disorder. CentoHear detects syndromic hearing loss, which accounts for 30% of genetic causes. It includes syndromes, such as Alport, Pendred, Waardenburg, Usher, and branchio-oto-renal. In addition, CentoHear detects non-syndromic hearing loss, which accounts for 70% of genetic causes. Both autosomal recessive and dominant cases are included in the panel.
|No. of genes:||199|