Scientific Publication 

Understanding DNA Alterations in Colorectal Cancer

Author(s): Kandaswamy, Krishna Kumar, PhD, Bauer, Dr. Peter, MD, Hühns, Maja, Nürnberg, Sylvia, Maletzki, Claudia, Prall, Friedrich

Germline and somatic DNA alterations may cause inherited diseases and/or cancer. While CENTOGENE’s routine diagnostic focus is on the former, we frequently address oncological questions in research settings. Deep sequencing of colorectal tumors in one such project provided unprecedented insights into the evolution of this type of cancer. The findings were recently published in Modern Pathology.

Germline and somatic DNA alterations may cause inherited diseases and/or cancer. While CENTOGENE’s routine diagnostic focus is on the former, we frequently address oncological questions in research settings. Deep sequencing of colorectal tumors in one such project provided unprecedented insights into the evolution of this type of cancer. The findings were recently published in Modern Pathology.


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