A Genetic Cause for Infectious Disease

Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease

While infectious diseases are commonly connected to environmental factors, genetic defects in some genes can strongly increase a person’s susceptibility to infections. Data generated at CENTOGENE helped to identify yet another example of this rare phenomenon. The findings, which revealed a novel disorder of the immune system, were published in the Proceedings of the National Academy of Sciences of the United States of America.


  • Tom Le Voyer
  • et al.