{"id":2227,"date":"2022-06-13T00:00:00","date_gmt":"2022-06-13T00:00:00","guid":{"rendered":"http:\/\/centogene.vl22350.dinaserver.com\/2227"},"modified":"2022-06-13T00:00:00","modified_gmt":"2022-06-13T00:00:00","slug":"centogene-%e5%92%8c-agios-%e6%89%a9%e5%a4%a7%e5%90%88%e4%bd%9c%ef%bc%8c%e5%85%b1%e5%90%8c%e6%8e%a8%e8%bf%9b-pryukyndr-mitapivat-%e7%9a%84%e4%b8%b4%e5%ba%8a%e5%bc%80%e5%8f%91%ef%bc%8c%e7%94%a8%e4%ba%8e","status":"publish","type":"post","link":"https:\/\/www.centogene.com\/zh\/centogene-and-agios-expand-partnership-for-clinical-development-of-pyrukyndr-mitapivat-to-treat-children-with-rare-blood-disease\/","title":{"rendered":"Centogene \u548c Agios \u6269\u5927\u5408\u4f5c\uff0c\u5171\u540c\u63a8\u8fdb PYRUKYND\u00ae\uff08mitapivat\uff09\u7684\u4e34\u5e8a\u5f00\u53d1\uff0c\u7528\u4e8e\u6cbb\u7597\u513f\u7ae5\u7f55\u89c1\u8840\u6db2\u75be\u75c5\u3002"},"content":{"rendered":"<p class=\"h3\">\u5171\u540c\u81f4\u529b\u4e8e\u7814\u53d1\u4e16\u754c\u4e0a\u9996\u4e2a\u9488\u5bf918\u5c81\u4ee5\u4e0b\u513f\u7ae5\u4e19\u916e\u9178\u6fc0\u9176\uff08\u201cPK\u201d\uff09\u7f3a\u4e4f\u75c7\u6839\u672c\u539f\u56e0\u7684\u6cbb\u7597\u65b9\u6cd5<br \/> &nbsp;<\/p>\n<ul>\n<li>\u6269\u5927\u5408\u4f5c\u8303\u56f4\uff0c\u7eb3\u5165 ACTIVATE-kids \u548c ACTIVATE-kidsT \u4e09\u671f\u7814\u7a76<\/li>\n<li>CENTOGENE\u7684\u57fa\u56e0\u68c0\u6d4b\u548c\u751f\u7269\u6570\u636e\u5e93\u53ef\u8bc6\u522b\u81f4\u75c5\u7a81\u53d8\uff0c\u5305\u62ecUGT1A1\u548cPKLR\u57fa\u56e0\uff0c\u5e76\u652f\u6301\u7cbe\u51c6\u8bca\u65ad\u3002<\/li>\n<\/ul>\n<p> <strong>\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u3001\u5fb7\u56fd\u7f57\u65af\u6258\u514b\u548c\u67cf\u6797\uff0c2022\u5e746\u670813\u65e5\uff08\u73af\u7403\u901a\u8baf\u793e\uff09<\/strong> \u4e13\u6ce8\u4e8e\u7f55\u89c1\u75c5\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u5546\u4e1a\u5316\u9636\u6bb5\u5173\u952e\u751f\u7269\u6570\u636e\u751f\u547d\u79d1\u5b66\u5408\u4f5c\u4f19\u4f34 Centogene NV\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aCNTG\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u5df2\u6269\u5927\u5176\u957f\u671f\u5408\u4f5c\u7684 PYRUKYND \u9879\u76ee\u3002<sup>\u00ae<\/sup> \uff08mitapivat\uff09\u4e0e Agios Pharmaceuticals, Inc.\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aAGIO\uff09\u5efa\u7acb\u5408\u4f5c\u5173\u7cfb\uff0c\u8be5\u516c\u53f8\u662f\u7ec6\u80de\u4ee3\u8c22\u9886\u57df\u7684\u9886\u5bfc\u8005\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u9488\u5bf9\u57fa\u56e0\u5b9a\u4e49\u75be\u75c5\u7684\u5f00\u521b\u6027\u7597\u6cd5\u3002.<\/p>\n<p>Agios \u7684 PYRUKYND<sup>\u00ae<\/sup> PYRUKYND \u662f\u4e00\u79cd\u9996\u521b\u7684\u3001\u9009\u62e9\u6027\u7684\u5c0f\u5206\u5b50\u4e19\u916e\u9178\u6fc0\u9176 (PK) \u6fc0\u6d3b\u5242\u30022022 \u5e74 2 \u6708\uff0cAgios \u516c\u53f8\u83b7\u5f97\u4e86\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u5bf9\u5176\u4ea7\u54c1\u7684\u6279\u51c6\u3002<sup>\u00ae<\/sup> \u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u5f15\u8d77\u7684\u6eb6\u8840\u6027\u8d2b\u8840\uff0c\u662f\u76ee\u524d\u552f\u4e00\u83b7\u6279\u7684\u9488\u5bf9\u8fd9\u79cd\u7f55\u89c1\u8840\u6db2\u75be\u75c5\u7684\u75be\u75c5\u4fee\u9970\u7597\u6cd5\u3002\u81ea 2015 \u5e74\u4ee5\u6765\uff0cCENTOGENE \u4e00\u76f4\u4e3a Agios \u516c\u53f8\u63d0\u4f9b\u57fa\u56e0\u68c0\u6d4b\u670d\u52a1\uff0c\u7528\u4e8e PYRUKYND \u7684\u4e34\u5e8a\u5f00\u53d1\u3002<sup>\u00ae<\/sup>.<\/p>\n<p>\u6839\u636e\u6269\u5c55\u540e\u7684\u534f\u8bae\uff0cCENTOGENE \u5c06\u4e3a Agios \u7684\u4e24\u9879\u5168\u7403\u5173\u952e\u6027 III \u671f\u4e34\u5e8a\u8bd5\u9a8c ACTIVATE-kids \u548c ACTIVATE-kidsT \u63d0\u4f9b\u96c6\u4e2d\u5f0f\u5b9e\u9a8c\u5ba4\u652f\u6301\u3002\u8fd9\u4e24\u9879\u8bd5\u9a8c\u65e8\u5728\u8bc4\u4f30\u7c73\u5854\u5339\u4f10\u7279 (mitapivat) \u5bf9 1 \u81f3 17 \u5c81\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7 (PK \u7f3a\u4e4f\u75c7) \u513f\u7ae5\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002CENTOGENE \u5c06\u7ee7\u7eed\u63d0\u4f9b\u57fa\u56e0\u68c0\u6d4b\uff0c\u4ee5\u5e2e\u52a9\u8bc6\u522b\u7814\u7a76\u53c2\u4e0e\u8005\u7684\u81f4\u75c5\u7a81\u53d8\uff0c\u5305\u62ec UGT1A1 \u548c PKLR \u57fa\u56e0\u3002ACTIVATE-kids \u548c ACTIVATE-kidsT III \u671f\u4e34\u5e8a\u8bd5\u9a8c\u65e8\u5728\u68c0\u9a8c PYRUKYND \u7684\u7597\u6548\u3002<sup>\u00ae<\/sup> \u5206\u522b\u9488\u5bf9\u672a\u63a5\u53d7\u5b9a\u671f\u8f93\u8840\u7684\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u60a3\u513f\u548c\u63a5\u53d7\u5b9a\u671f\u8f93\u8840\u7684\u60a3\u513f\u3002Agios \u5c06\u8d1f\u8d23\u534f\u8c03\u5e76\u627f\u62c5\u8fd9\u4e9b\u9879\u76ee\u7684\u8d39\u7528\uff1b\u5176\u4ed6\u8d22\u52a1\u7ec6\u8282\u672a\u4e88\u62ab\u9732\u3002.<\/p>\n<p>\u201c\u6211\u4eec\u4e0eAgios\u7684\u6210\u529f\u5408\u4f5c\u5df2\u63a8\u52a8\u8fd9\u4e00\u9996\u521bPK\u6fc0\u6d3b\u5242\u5728\u4e34\u5e8a\u4e0a\u53d6\u5f97\u4e86\u4ee4\u4eba\u77a9\u76ee\u7684\u8fdb\u5c55\uff0c\u6709\u671b\u6210\u4e3a\u6cbb\u7597\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u60a3\u513f\u7684\u7597\u6cd5\u3002\u8be5\u60a3\u513f\u7fa4\u4f53\u76ee\u524d\u6cbb\u7597\u9700\u6c42\u4e0d\u8db3\uff0c\u4e9f\u9700\u65b0\u7684\u6cbb\u7597\u65b9\u6848\u3002\u6b64\u6b21\u5408\u4f5c\u7684\u62d3\u5c55\u8fdb\u4e00\u6b65\u5370\u8bc1\u4e86\u6211\u4eec\u6709\u80fd\u529b\u63a8\u52a8\u65b0\u578b\u6cbb\u7597\u65b9\u6848\u7684\u7814\u53d1\uff0c\u4ece\u800c\u6539\u5584\u5168\u7403\u60a3\u8005\u7684\u5065\u5eb7\u72b6\u51b5\u3002\u201dCENTOGENE\u9996\u5e2d\u6267\u884c\u5b98Kim Stratton\u8868\u793a\uff0c\u201c\u51ed\u501f\u6211\u4eec\u65e0\u4e0e\u4f26\u6bd4\u7684\u8bca\u65ad\u670d\u52a1\u548c\u7531CENTOGENE\u751f\u7269\u6570\u636e\u5e93\uff08\u5168\u7403\u6700\u5927\u7684\u7f55\u89c1\u75c5\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5b58\u50a8\u5e93\uff09\u63d0\u4f9b\u652f\u6301\u7684\u6d1e\u5bdf\uff0c\u6211\u4eec\u80fd\u591f\u4e3a\u751f\u7269\u6280\u672f\u548c\u5236\u836f\u5408\u4f5c\u4f19\u4f34\u63d0\u4f9b\u4e34\u5e8a\u5f00\u53d1\u4e2d\u81f3\u5173\u91cd\u8981\u7684\u751f\u7269\u6570\u636e\u3002\u201d<\/p>\n<p>Agios\u9996\u5e2d\u533b\u7597\u5b98Sarah Gheuens\u533b\u5b66\u535a\u58eb\u8868\u793a\uff1a\u201c\u968f\u7740\u6211\u4eec\u5168\u7403\u8303\u56f4\u5185\u9488\u5bf9\u513f\u7ae5\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u7684\u5173\u952e\u6027\u4e34\u5e8a\u8bd5\u9a8c\u7684\u63a8\u8fdb\uff0c\u6211\u4eec\u5f88\u9ad8\u5174\u80fd\u591f\u6269\u5927\u4e0eCENTOGENE\u7684\u5408\u4f5c\uff0c\u4f7f\u9996\u4e2a\u6f5c\u5728\u7597\u6cd5\u8ddd\u79bb\u9020\u798f\u8fd9\u4e9b\u513f\u7ae5\u53ca\u5176\u5bb6\u5ead\u66f4\u8fd1\u4e00\u6b65\u3002\u5728Agios\uff0c\u6211\u4eec\u6df1\u77e5\u5353\u8d8a\u7684\u79d1\u5b66\u7814\u7a76\u9700\u8981\u4e16\u754c\u4e00\u6d41\u7684\u5408\u4f5c\u3002\u52a0\u901f\u548c\u7b80\u5316\u6211\u4eec\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5bf9\u4e8e\u5c3d\u53ef\u80fd\u9ad8\u6548\u5730\u5c06\u521b\u65b0\u7597\u6cd5\u5e26\u7ed9\u60a3\u8005\u81f3\u5173\u91cd\u8981\uff0c\u800cCENTOGENE\u7684\u89e3\u51b3\u65b9\u6848\u4f7f\u5176\u6210\u4e3a\u8be5\u9879\u76ee\u7684\u7406\u60f3\u5408\u4f5c\u4f19\u4f34\u3002\u201d<\/p>\n<p>\u5728\u5408\u4f5c\u6846\u67b6\u4e0b\uff0cCENTOGENE \u7684\u4e13\u6709 CentoCard \u5c06\u88ab\u7eb3\u5165\u5408\u4f5c\u8303\u56f4\u3002<sup>\u00ae<\/sup> \u5e72\u8840\u6591\u6280\u672f\u4e3a\u4e2d\u5fc3\u8bca\u65ad\u68c0\u6d4b\u63d0\u4f9b\u4e86\u4fbf\u6377\u7684\u7269\u6d41\u652f\u6301\u3002\u6b64\u6b21\u5408\u4f5c\u7684\u5173\u952e\u8d44\u4ea7\u5305\u62ec CENTOGENE \u751f\u7269\u6570\u636e\u5e93\u3001\u57fa\u4e8e 15 \u5e74\u4ee5\u4e0a\u7ecf\u9a8c\u79ef\u7d2f\u7684\u8bca\u65ad\u4e13\u4e1a\u77e5\u8bc6\uff0c\u4ee5\u53ca\u516c\u53f8\u57fa\u4e8e\u591a\u7ec4\u5b66\u7684\u5e73\u53f0\u2014\u2014\u8be5\u5e73\u53f0\u7387\u5148\u5b9e\u73b0\u4e86\u76ee\u524d\u5e02\u573a\u4e0a\u5546\u4e1a\u5316\u591a\u7ec4\u5b66\u4ea7\u54c1\u7684\u666e\u53ca\u3002.<\/p>\n<p>2015\u5e74\uff0cCENTOGENE\u6700\u521d\u4e0eAgios\u516c\u53f8\u8fbe\u6210\u534f\u8bae\uff0c\u4e3aAgios\u516c\u53f8\u7684\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u4e34\u5e8a\u9879\u76ee\u63d0\u4f9b\u652f\u6301\u3002\u53bb\u5e74\uff0c\u8be5\u5408\u540c\u6269\u5927\u4e86\u8303\u56f4\uff0c\u6db5\u76d6\u5730\u4e2d\u6d77\u8d2b\u8840\u548c\u9570\u72b6\u7ec6\u80de\u75c5\u7684\u66f4\u591a\u4e34\u5e8a\u8bd5\u9a8c\u652f\u6301\u3002.<\/p>\n<h3>\u5173\u4e8e PYRUKYND\u00ae\uff08\u7c73\u5854\u76ae\u4f10\u7279\uff09<\/h3>\n<p>\u5421\u54af\u70f7<sup>\u00ae<\/sup> PYRUKYND \u662f\u4e00\u79cd\u4e19\u916e\u9178\u6fc0\u9176\u6fc0\u6d3b\u5242\uff0c\u9002\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u4e19\u916e\u9178\u6fc0\u9176 (PK) \u7f3a\u4e4f\u75c7\u5f15\u8d77\u7684\u6eb6\u8840\u6027\u8d2b\u8840\u30022022 \u5e74 2 \u6708\uff0cAgios \u516c\u53f8\u83b7\u5f97\u4e86\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u5bf9\u5176\u4ea7\u54c1 PYRUKYND \u7684\u6279\u51c6\u3002<sup>\u00ae<\/sup> \u8be5\u836f\u7269\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u5f15\u8d77\u7684\u6eb6\u8840\u6027\u8d2b\u8840\uff0c\u662f\u76ee\u524d\u552f\u4e00\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u8fd9\u79cd\u7f55\u89c1\u8840\u6db2\u75be\u75c5\u7684\u6210\u4eba\u60a3\u8005\u7684\u75be\u75c5\u6539\u5584\u7597\u6cd5\u3002\u6b64\u5916\uff0c\u6839\u636e\u513f\u79d1\u7814\u7a76\u8ba1\u5212 (PIP)\uff0c\u8be5\u836f\u7269\u8fd8\u83b7\u5f97\u4e86\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40 (EMA) \u7684\u8c41\u514d\uff0c\u53ef\u7528\u4e8e\u6cbb\u7597\u51fa\u751f\u81f3 1 \u5c81\u4ee5\u4e0b\u513f\u7ae5\u7684\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u3002.<\/p>\n<h3>\u5173\u4e8ePK\u7f3a\u4e4f\u75c7<\/h3>\n<p>\u4e19\u916e\u9178\u6fc0\u9176\uff08PK\uff09\u7f3a\u4e4f\u75c7\u662f\u4e00\u79cd\u7f55\u89c1\u7684\u9057\u4f20\u6027\u75be\u75c5\uff0c\u8868\u73b0\u4e3a\u6162\u6027\u6eb6\u8840\u6027\u8d2b\u8840\uff0c\u5373\u7ea2\u7ec6\u80de\u52a0\u901f\u7834\u574f\u3002PKLR\u57fa\u56e0\u7684\u9057\u4f20\u7a81\u53d8\u5bfc\u81f4\u7ea2\u7ec6\u80de\u5185\u7ec6\u80de\u80fd\u91cf\u4e0d\u8db3\uff0c\u8868\u73b0\u4e3aPKR\u9176\u6d3b\u6027\u964d\u4f4e\u3001\u4e09\u78f7\u9178\u817a\u82f7\uff08ATP\uff09\u6c34\u5e73\u4e0b\u964d\u4ee5\u53ca\u4e0a\u6e38\u4ee3\u8c22\u7269\uff08\u5305\u62ec2,3-\u4e8c\u78f7\u9178\u7518\u6cb9\u9178\uff082,3-DPG\uff09\uff09\u7684\u79ef\u7d2f\u3002.<\/p>\n<p>\u5728\u7f8e\u56fd\u548c\u6b27\u76df5\u56fd\uff0c\u5927\u7ea6\u67093000-8000\u4eba\u60a3\u6709PK\u7f3a\u4e4f\u75c7\u3002PK\u7f3a\u4e4f\u75c7\u53ef\u80fd\u5bfc\u81f4\u4e25\u91cd\u7684\u5e76\u53d1\u75c7\uff0c\u5982\u80ba\u52a8\u8109\u9ad8\u538b\u3001\u9ad3\u5916\u9020\u8840\u548c\u9aa8\u8d28\u758f\u677e\u75c7\u3002.<\/p>\n<p>\u5982\u9700\u4e86\u89e3\u66f4\u591a\u5173\u4e8e ACTIVATE-kids \u548c ACTIVATE-kidsT \u4e34\u5e8a\u8bd5\u9a8c\u7684\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\uff1a <a href=\"https:\/\/www.agios.com\/patients-partners\/patients-caregivers\/clinical-trials\/ \" target=\"_blank\" title=\"Agios ACTIVATE-kids \u548c ACTIVATE-kidsT \u4e34\u5e8a\u8bd5\u9a8c\">https:\/\/www.agios.com\/patients-partners\/patients-caregivers\/clinical-trials\/ <\/a><\/p>\n<h3>\u5173\u4e8e\u963f\u5409\u5965\u65af<\/h3>\n<p>Agios\u662f\u4e00\u5bb6\u4ee5\u4eba\u4e3a\u672c\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\u3002Agios\u56e2\u961f\u4e0e\u60a3\u8005\u7fa4\u4f53\u3001\u533b\u7597\u4e13\u4e1a\u4eba\u58eb\u3001\u5408\u4f5c\u4f19\u4f34\u548c\u540c\u4e8b\u5efa\u7acb\u7d27\u5bc6\u7684\u8054\u7cfb\uff0c\u81f4\u529b\u4e8e\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u63d0\u4f9b\u9488\u5bf9\u57fa\u56e0\u75be\u75c5\u7684\u7597\u6cd5\u3002\u5728\u7f8e\u56fd\uff0cAgios\u9500\u552e\u4e00\u79cd\u9996\u521b\u7684\u4e19\u916e\u9178\u6fc0\u9176\uff08PK\uff09\u6fc0\u6d3b\u5242\uff0c\u7528\u4e8e\u6cbb\u7597\u6210\u4ebaPK\u7f3a\u4e4f\u75c7\uff0c\u8fd9\u662f\u9996\u4e2a\u9488\u5bf9\u8fd9\u79cd\u7f55\u89c1\u3001\u7ec8\u8eab\u4e14\u81f4\u6b8b\u6027\u6eb6\u8840\u6027\u8d2b\u8840\u7684\u75be\u75c5\u4fee\u9970\u7597\u6cd5\u3002\u51ed\u501f\u5728\u7ec6\u80de\u4ee3\u8c22\u9886\u57df\u7684\u9886\u5148\u5730\u4f4d\uff0cAgios\u6b63\u5728\u63a8\u8fdb\u4e00\u7cfb\u5217\u5f3a\u5927\u7684\u5728\u7814\u836f\u7269\u4e34\u5e8a\u7ba1\u7ebf\uff0c\u5176\u4e2d\u5305\u62ec\u9488\u5bf9\u03b1-\u548c\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u3001\u9570\u72b6\u7ec6\u80de\u75c5\u3001\u513f\u7ae5PK\u7f3a\u4e4f\u75c7\u548cMDS\u76f8\u5173\u6027\u8d2b\u8840\u7684\u5728\u7814\u548c\u8ba1\u5212\u4e2d\u7684\u9879\u76ee\u3002\u9664\u4e86\u4e34\u5e8a\u7ba1\u7ebf\u5916\uff0cAgios\u8fd8\u6709\u591a\u4e2a\u5904\u4e8e\u4e34\u5e8a\u524d\u5f00\u53d1\u9636\u6bb5\u7684\u5728\u7814\u7597\u6cd5\uff0c\u4ee5\u53ca\u4e00\u652f\u5728\u7ec6\u80de\u4ee3\u8c22\u548c\u9057\u4f20\u5b66\u9886\u57df\u62e5\u6709\u65e0\u53ef\u6bd4\u62df\u7684\u4e13\u4e1a\u77e5\u8bc6\u7684\u884c\u4e1a\u9886\u5148\u7684\u7814\u7a76\u56e2\u961f\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee\u516c\u53f8\u7f51\u7ad9\u3002 <a href=\"https:\/\/www.agios.com\/\" target=\"_blank\" title=\"\u963f\u5409\u5965\u65af\">https:\/\/www.agios.com\/<\/a><\/p>\n<h3>\u5173\u4e8e CENTOGENE<\/h3>\n<p>CENTOGENE\u81f4\u529b\u4e8e\u7f55\u89c1\u75c5\u7684\u8bca\u65ad\u548c\u7814\u7a76\uff0c\u901a\u8fc7\u8f6c\u5316\u771f\u5b9e\u4e16\u754c\u7684\u4e34\u5e8a\u3001\u9057\u4f20\u548c\u591a\u7ec4\u5b66\u6570\u636e\uff0c\u5b9e\u73b0\u7f55\u89c1\u75c5\u7684\u8bca\u65ad\u3001\u7406\u89e3\u548c\u6cbb\u7597\u3002\u6211\u4eec\u7684\u76ee\u6807\u662f\u5229\u7528\u6211\u4eec\u4e30\u5bcc\u7684\u7f55\u89c1\u75c5\u77e5\u8bc6\u548c\u6570\u636e\uff0c\u4e3a\u6cbb\u7597\u51b3\u7b56\u63d0\u4f9b\u5408\u7406\u7684\u4f9d\u636e\uff0c\u5e76\u52a0\u901f\u65b0\u578b\u5b64\u513f\u836f\u7684\u7814\u53d1\u3002CENTOGENE\u5df2\u5f00\u53d1\u51fa\u4e00\u4e2a\u5168\u7403\u4e13\u6709\u7684\u7f55\u89c1\u75c5\u5e73\u53f0\uff0c\u8be5\u5e73\u53f0\u57fa\u4e8e\u6211\u4eec\u62e5\u6709\u8d85\u8fc765\u4e07\u540d\u6765\u81ea120\u591a\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u7684\u4e2a\u4f53\u7684\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5b58\u50a8\u5e93\u3002.<\/p>\n<p>\u516c\u53f8\u5e73\u53f0\u5305\u542b\u53cd\u6620\u5168\u7403\u4eba\u7fa4\u7684\u6d41\u884c\u75c5\u5b66\u3001\u8868\u578b\u548c\u9057\u4f20\u6570\u636e\uff0c\u4ee5\u53ca\u60a3\u8005\u8840\u6db2\u6837\u672c\u548c\u7ec6\u80de\u57f9\u517b\u7269\u7684\u751f\u7269\u6837\u672c\u5e93\u3002CENTOGENE \u8ba4\u4e3a\uff0c\u8fd9\u662f\u76ee\u524d\u552f\u4e00\u4e13\u6ce8\u4e8e\u5bf9\u591a\u5c42\u6b21\u6570\u636e\u8fdb\u884c\u5168\u9762\u5206\u6790\u4ee5\u589e\u8fdb\u5bf9\u7f55\u89c1\u9057\u4f20\u75be\u75c5\u7406\u89e3\u7684\u5e73\u53f0\u3002\u8be5\u5e73\u53f0\u80fd\u591f\u66f4\u597d\u5730\u8bc6\u522b\u548c\u5206\u5c42\u60a3\u8005\u53ca\u5176\u6f5c\u5728\u75be\u75c5\uff0c\u4ece\u800c\u4fc3\u8fdb\u548c\u52a0\u901f\u5b64\u513f\u836f\u7684\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u5e94\u7528\u3002\u622a\u81f3 2021 \u5e74 12 \u6708 31 \u65e5\uff0c\u516c\u53f8\u5df2\u4e0e 30 \u591a\u5bb6\u5236\u836f\u516c\u53f8\u5f00\u5c55\u5408\u4f5c\u3002.<\/p>\n<p>\u5173\u6ce8\u6211\u4eec <a href=\"https:\/\/de.linkedin.com\/company\/centogene\" target=\"_blank\" title=\"LinkedIn\">LinkedIn<\/a>.&nbsp;<\/p>\n<h3>\u524d\u77bb\u6027\u58f0\u660e<\/h3>\n<p>\u672c\u65b0\u95fb\u7a3f\u5305\u542b\u7f8e\u56fd\u8054\u90a6\u8bc1\u5238\u6cd5\u610f\u4e49\u4e0a\u7684\u201c\u524d\u77bb\u6027\u9648\u8ff0\u201d\u3002\u672c\u65b0\u95fb\u7a3f\u4e2d\u975e\u5386\u53f2\u4e8b\u5b9e\u7684\u9648\u8ff0\u5747\u4e3a\u524d\u77bb\u6027\u9648\u8ff0\uff0c\u8bf8\u5982\u201c\u9884\u671f\u201d\u3001\u201c\u76f8\u4fe1\u201d\u3001\u201c\u7ee7\u7eed\u201d\u3001\u201c\u671f\u671b\u201d\u3001\u201c\u4f30\u8ba1\u201d\u3001\u201c\u6253\u7b97\u201d\u3001\u201c\u9884\u8ba1\u201d\u7b49\u8bcd\u8bed\u4ee5\u53ca\u7c7b\u4f3c\u8868\u8fbe\u548c\u8868\u793a\u5c06\u6765\u65f6\u6216\u6761\u4ef6\u7684\u52a8\u8bcd\uff0c\u4f8b\u5982\u201c\u5c06\u201d\u3001\u201c\u4f1a\u201d\u3001\u201c\u5e94\u8be5\u201d\u3001\u201c\u53ef\u80fd\u201d\u3001\u201c\u6216\u8bb8\u201d\u3001\u201c\u53ef\u4ee5\u201d\u7b49\uff0c\u901a\u5e38\u7528\u4e8e\u8bc6\u522b\u524d\u77bb\u6027\u9648\u8ff0\u3002\u6b64\u7c7b\u524d\u77bb\u6027\u9648\u8ff0\u6d89\u53ca\u5df2\u77e5\u548c\u672a\u77e5\u7684\u98ce\u9669\u3001\u4e0d\u786e\u5b9a\u6027\u4ee5\u53ca\u5176\u4ed6\u91cd\u8981\u56e0\u7d20\uff0c\u8fd9\u4e9b\u56e0\u7d20\u53ef\u80fd\u5bfc\u81f4CENTOGENE\u7684\u5b9e\u9645\u4e1a\u7ee9\u3001\u8868\u73b0\u6216\u6210\u5c31\u4e0e\u524d\u77bb\u6027\u9648\u8ff0\u4e2d\u660e\u793a\u6216\u6697\u793a\u7684\u4efb\u4f55\u672a\u6765\u4e1a\u7ee9\u3001\u8868\u73b0\u6216\u6210\u5c31\u5b58\u5728\u91cd\u5927\u5dee\u5f02\u3002\u6b64\u7c7b\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\uff1a\u4e0d\u5229\u7684\u7ecf\u6d4e\u548c\u5730\u7f18\u653f\u6cbb\u72b6\u51b5\u4ee5\u53ca\u5168\u7403\u91d1\u878d\u5e02\u573a\u7684\u4e0d\u7a33\u5b9a\u548c\u6ce2\u52a8\uff1b\u73b0\u884c\u548c\u62df\u8bae\u7684\u6cd5\u5f8b\u3001\u6cd5\u89c4\u548c\u653f\u5e9c\u653f\u7b56\u53ef\u80fd\u53d1\u751f\u7684\u53d8\u5316\uff1b\u884c\u4e1a\u7ade\u4e89\u52a0\u5267\u548c\u6574\u5408\u5e26\u6765\u7684\u538b\u529b\uff1b\u76d1\u7ba1\u5ba1\u6279\uff08\u5305\u62ec\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u5ba1\u6279\uff09\u7684\u8d39\u7528\u548c\u4e0d\u786e\u5b9a\u6027\uff1b\u6211\u4eec\u5bf9\u7b2c\u4e09\u65b9\u548c\u5408\u4f5c\u4f19\u4f34\u7684\u4f9d\u8d56\uff08\u5305\u62ec\u6211\u4eec\u7ba1\u7406\u589e\u957f\u548c\u5efa\u7acb\u65b0\u5ba2\u6237\u5173\u7cfb\u7684\u80fd\u529b\uff09\uff1b\u6211\u4eec\u5bf9\u7f55\u89c1\u75c5\u884c\u4e1a\u7684\u4f9d\u8d56\uff1b\u6211\u4eec\u7ba1\u7406\u56fd\u9645\u6269\u5f20\u7684\u80fd\u529b\uff1b\u6211\u4eec\u5bf9\u5173\u952e\u4eba\u5458\u7684\u4f9d\u8d56\uff1b\u6211\u4eec\u5bf9\u77e5\u8bc6\u4ea7\u6743\u4fdd\u62a4\u7684\u4f9d\u8d56\uff1b\u6c47\u7387\u5f71\u54cd\u5bfc\u81f4\u7684\u7ecf\u8425\u4e1a\u7ee9\u6ce2\u52a8\uff1b\u6211\u4eec\u7cbe\u7b80\u73b0\u91d1\u4f7f\u7528\u7684\u80fd\u529b\uff1b\u6211\u4eec\u5bf9\u989d\u5916\u878d\u8d44\u7684\u9700\u6c42\uff1b\u6216\u5176\u4ed6\u56e0\u7d20\u3002\u6709\u5173\u53ef\u80fd\u5bfc\u81f4\u5b9e\u9645\u7ed3\u679c\u4e0e\u8fd9\u4e9b\u524d\u77bb\u6027\u58f0\u660e\u4e2d\u6240\u8868\u8fbe\u7684\u7ed3\u679c\u5b58\u5728\u5dee\u5f02\u7684\u98ce\u9669\u548c\u4e0d\u786e\u5b9a\u6027\uff0c\u4ee5\u53ca\u4e0eCENTOGENE\u4e1a\u52a1\u76f8\u5173\u7684\u603b\u4f53\u98ce\u9669\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8bf7\u53c2\u9605CENTOGENE\u4e8e2022\u5e743\u670830\u65e5\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\uff08\u201cSEC\u201d\uff09\u63d0\u4ea4\u768420-F\u8868\u683c\u53ca\u5176\u540e\u7eed\u6587\u4ef6\u4e2d\u5217\u51fa\u7684CENTOGENE\u98ce\u9669\u56e0\u7d20\u3002\u672c\u65b0\u95fb\u7a3f\u4e2d\u5305\u542b\u7684\u4efb\u4f55\u524d\u77bb\u6027\u58f0\u660e\u4ec5\u4ee3\u8868\u622a\u81f3\u672c\u65b0\u95fb\u7a3f\u53d1\u5e03\u4e4b\u65e5\u7684\u4fe1\u606f\uff0cCENTOGENE\u660e\u786e\u58f0\u660e\u4e0d\u627f\u62c5\u4efb\u4f55\u66f4\u65b0\u4efb\u4f55\u524d\u77bb\u6027\u58f0\u660e\u7684\u4e49\u52a1\uff0c\u65e0\u8bba\u662f\u56e0\u4e3a\u65b0\u4fe1\u606f\u3001\u672a\u6765\u4e8b\u4ef6\u6216\u5176\u4ed6\u539f\u56e0\u3002.<\/p>\n<h4 class=\"h3\">\u5a92\u4f53\u8054\u7cfb\u4eba<\/h4>\n<h5>\u4e2d\u5fc3\u57fa\u56e0<\/h5>\n<p>\u672c\u00b7\u83b1\u683c<br \/> \u4f01\u4e1a\u4f20\u64ad\u90e8&nbsp;<br \/> <a href=\"mailto:press@centogene.com\" title=\"\u5199\u4e00\u5c01\u7535\u5b50\u90ae\u4ef6\">press(at)centogene(dot)com<\/a><\/p>\n<p>\u4f26\u7eb3\u7279\u00b7\u65af\u7279\u8d56\u8d1d\u5c14<br \/> \u6295\u8d44\u8005\u5173\u7cfb<br \/> <a href=\"mailto:investor.relations@centogene.com\" title=\"\u5199\u4e00\u5c01\u7535\u5b50\u90ae\u4ef6\">investor.relations(at)centogene(dot)com <\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Centogene \u548c Agios \u6269\u5927\u5408\u4f5c\uff0c\u5171\u540c\u63a8\u8fdb 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