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  1. A controversy in Parkinsonism research

A controversy in Parkinsonism research

Ellen Sidransky 1 David Arkadir, Dr. 2, 3 Dr. Peter Bauer, MD 4 Tama Dinur, PhD 5 Grisel Lopez 1 Prof. Arndt Rolfs, MD 4 Ari Zimran, MD 2, 5
1 National Institutes of Health 2 The Hebrew University of Jerusalem 3 Hadassah Medical Center 4 CENTOGENE AG 5 Shaare Zedek Medical Center (SZMC), Jerusalem
November 11, 2019

Substrate reduction therapy for GBA1-associated Parkinsonism: Are we betting on the wrong mouse?

Parkinson disease (PD) can be associated with mutations that are usually found in patients with Gaucher disease (GD). Treatment options for GD are therefore considered also for PD, but there are reasons to question this approach. A pertinent commentary by experts in the field, which included the CEO and the CSO of CENTOGENE, was recently published in the journal Movement Disorders.