{"id":2445,"date":"2016-12-15T00:00:00","date_gmt":"2016-12-15T00:00:00","guid":{"rendered":"http:\/\/centogene.vl22350.dinaserver.com\/2445"},"modified":"2016-12-15T00:00:00","modified_gmt":"2016-12-15T00:00:00","slug":"o-proximo-lancamento-do-centomdr-31","status":"publish","type":"post","link":"https:\/\/www.centogene.com\/pt\/the-upcoming-release-of-centomdr-31\/","title":{"rendered":"O pr\u00f3ximo lan\u00e7amento do CentoMD\u00ae 3.1"},"content":{"rendered":"<p>Com o lan\u00e7amento do CentoMD\u00ae 3.1 no final de setembro de 2016, a CENTOGENE disponibilizar\u00e1 informa\u00e7\u00f5es gen\u00e9ticas e dados cl\u00ednicos de mais de 100.000 pessoas em todo o mundo. As informa\u00e7\u00f5es e os dados provenientes desse cat\u00e1logo global de informa\u00e7\u00f5es gen\u00e9ticas permitem uma interpreta\u00e7\u00e3o muito mais precisa dos dados gen\u00e9ticos e, por estarem vinculados a dados cl\u00ednicos, melhoram o atendimento m\u00e9dico.<\/p>\n<p>O CentoMD\u00ae \u2013 o maior banco de dados gen\u00e9ticos do mundo para doen\u00e7as gen\u00e9ticas raras \u2013 mant\u00e9m aproximadamente 3 milh\u00f5es de alelos identificados, polimorfismos associados a doen\u00e7as, polimorfismos benignos e outras variantes conhecidas de significado indeterminado, dos quais cerca de 60% s\u00e3o dados n\u00e3o publicados. O CentoMD\u00ae \u00e9 atualizado trimestralmente com novas muta\u00e7\u00f5es identificadas no CENTOGENE e com base em publica\u00e7\u00f5es cient\u00edficas.<\/p>\n<p>A interpreta\u00e7\u00e3o dos resultados do sequenciamento continua sendo a etapa mais complexa e dif\u00edcil no diagn\u00f3stico gen\u00e9tico. Como um excelente pipeline de bioinform\u00e1tica para filtragem e anota\u00e7\u00e3o de variantes \u00e9 fundamental para a produ\u00e7\u00e3o de dados de qualidade, a parte essencial do processo diagn\u00f3stico \u00e9 a classifica\u00e7\u00e3o das variantes quanto \u00e0 sua relev\u00e2ncia cl\u00ednica para o paciente.<\/p>\n<p>\u201cOs dados gen\u00e9ticos na era do sequenciamento completo do exoma e do genoma resultam em centenas de milhares de novas variantes com significado cl\u00ednico desconhecido. Com o CentoMD\u00ae, permitimos o acesso a informa\u00e7\u00f5es de casos reais de uma coorte global de pacientes, combinadas em conjuntos de dados cuidadosamente selecionados \u2013 e transformamos informa\u00e7\u00f5es anal\u00edticas em resultados m\u00e9dicos acion\u00e1veis\u201d, afirmou o Professor Arndt Rolfs, CEO da CENTOGENE.<\/p>","protected":false},"excerpt":{"rendered":"<p>Com o lan\u00e7amento previsto do CentoMD\u00ae 3.1 no final de setembro de 2016, a CENTOGENE divulgar\u00e1 informa\u00e7\u00f5es gen\u00e9ticas e dados cl\u00ednicos de mais de 100.000 pessoas em todo o mundo.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2445","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This 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