{"id":2410,"date":"2018-05-29T00:00:00","date_gmt":"2018-05-29T00:00:00","guid":{"rendered":"http:\/\/centogene.vl22350.dinaserver.com\/2410"},"modified":"2018-05-29T00:00:00","modified_gmt":"2018-05-29T00:00:00","slug":"acordo-com-a-aldeyra-therapeutics","status":"publish","type":"post","link":"https:\/\/www.centogene.com\/pt\/agreement-with-aldeyra-therapeutics\/","title":{"rendered":"Acordo com a Aldeyra Therapeutics"},"content":{"rendered":"

A CENTOGENE anunciou hoje que firmou um acordo com Aldeyra Therapeutics Inc<\/a>., uma empresa de biotecnologia que desenvolve medicamentos de \u00faltima gera\u00e7\u00e3o para melhorar a vida de pacientes com doen\u00e7as imunomediadas.<\/p>\n

Nos termos do acordo, a CENTOGENE colaborar\u00e1 com a Aldeyra para identificar globalmente pacientes com SLS e compreender o espectro cl\u00ednico dessa doen\u00e7a. O objetivo do acordo \u00e9 apoiar m\u00e9dicos e pacientes no diagn\u00f3stico precoce por meio de testes gen\u00e9ticos que podem levar \u00e0 identifica\u00e7\u00e3o de novas terapias e aumentar a conscientiza\u00e7\u00e3o sobre a doen\u00e7a.<\/p>\n

\u201cA maioria dos pacientes com doen\u00e7as heredit\u00e1rias raras enfrenta uma longa jornada diagn\u00f3stica antes de ter certeza sobre sua condi\u00e7\u00e3o. O conhecimento global sobre a S\u00edndrome de Lynch (SLS) \u00e9 muito limitado, o que significa que os m\u00e9dicos muitas vezes nem sequer pensam na SLS ao se depararem com os sintomas do paciente e, consequentemente, n\u00e3o realizam os testes gen\u00e9ticos necess\u00e1rios. Esse desafio \u00e9 um excelente exemplo de como nosso banco de dados de conhecimento global e abrangente (CentoMD\u00ae) pode trazer um enorme benef\u00edcio como uma solu\u00e7\u00e3o universal de sa\u00fade para a comunidade de doen\u00e7as raras\u201d, disse o Dr. Arndt Rolfs, CEO e fundador da CENTOGENE.<\/p>\n

\u201cA parceria com a CENTOGENE complementa o Registro de Pacientes com SLS da Aldeyra, que foi criado para unir pacientes e aumentar a conscientiza\u00e7\u00e3o global sobre a doen\u00e7a\u201d, disse David Clark, MD, MRCP, AFPM, Diretor M\u00e9dico da Aldeyra. \u201cAl\u00e9m disso, ter acesso ao banco de dados gen\u00e9ticos de pacientes com SLS da CENTOGENE demonstra o papel fundamental da gen\u00e9tica na identifica\u00e7\u00e3o de pacientes e no desenvolvimento de medicamentos para doen\u00e7as para as quais n\u00e3o existem tratamentos.\u201d<\/p>\n

A S\u00edndrome de Slatic-Leydig (SLS) \u00e9 herdada de forma autoss\u00f4mica recessiva e os pacientes apresentam um amplo espectro de sintomas, incluindo: ictiose (pele severamente seca, espessa e escamosa), espa\u00e7amento entre as pernas e atraso cognitivo. Pacientes com SLS n\u00e3o conseguem metabolizar adequadamente mol\u00e9culas chamadas alde\u00eddos graxos, resultando em um ac\u00famulo anormal dessas mol\u00e9culas e, consequentemente, nos sintomas da doen\u00e7a. Atualmente, n\u00e3o existe tratamento aprovado pela FDA para a SLS.<\/p>\n

Sobre a CENTOGENE<\/h5>\n

A CENTOGENE utiliza o poder do conhecimento gen\u00e9tico para melhorar a qualidade de vida de pacientes com doen\u00e7as gen\u00e9ticas raras. Conseguimos isso por meio do conhecimento gerado por nossos servi\u00e7os globais de testes diagn\u00f3sticos, que incorporam a diversidade global, o banco de dados propriet\u00e1rio l\u00edder mundial em interpreta\u00e7\u00e3o gen\u00e9tica humana, o CentoMD\u00ae, e solu\u00e7\u00f5es para empresas farmac\u00eauticas que desenvolvem medicamentos \u00f3rf\u00e3os que transformam vidas.<\/p>\n

Como uma das maiores e mais diversificadas empresas de testes gen\u00e9ticos do mundo, a CENTOGENE dedica-se a transformar a ci\u00eancia da informa\u00e7\u00e3o gen\u00e9tica em solu\u00e7\u00f5es e esperan\u00e7a para pacientes e suas fam\u00edlias.<\/p>\n

www.centogene.com<\/a> www.centoMD.com<\/a><\/p>\n

Sobre a S\u00edndrome de Sj\u00f6gren-Larsson<\/h5>\n

A s\u00edndrome de Sj\u00f6gren-Larsson \u00e9 um erro inato raro do metabolismo de alde\u00eddos causado por muta\u00e7\u00f5es na enzima desidrogenase de alde\u00eddos de \u00e1cidos graxos, levando a n\u00edveis elevados de alde\u00eddos graxos t\u00f3xicos que se acredita contribu\u00edrem para ictiose grave (pele escamosa, espessa e seca), dist\u00farbios neurol\u00f3gicos e doen\u00e7as da retina. N\u00e3o existe terapia para a s\u00edndrome de Sj\u00f6gren-Larsson aprovada pela Food and Drug Administration (FDA) dos EUA.<\/p>","protected":false},"excerpt":{"rendered":"

A CENTOGENE anunciou hoje que firmou um acordo com a Aldeyra Therapeutics Inc., uma empresa de biotecnologia que desenvolve medicamentos de \u00faltima gera\u00e7\u00e3o para melhorar a vida de pacientes com doen\u00e7as imunomediadas.<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2410","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"yoast_head":"\nAgreement with Aldeyra Therapeutics | CENTOGENE<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.centogene.com\/pt\/acordo-com-a-aldeyra-therapeutics\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" 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