Biomarker

CENTOGENE works alongside academic and industrial partners, as well as patient organizations, to develop new diagnostic assays and biomarkers that can help to diagnose and monitor diseases.

  1. Biomarker

Diagnosis, prediction and therapy monitoring

Our biomarker portfolio enables you to diagnose initially and monitor constantly with adherence to

  • Realistic reflection of the burden of the disease
  • Solid basis to reflect therapeutic measures
  • Link to clinical manifestation
  • Easy and reliable quantification

Downloads available

  • Typical findings in LSD - Biomarker (poster)

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  • Request form - Biochemical and biomarker testing

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CENTOGENE’s biomarkers

  • Easy analysis using DBS (dried blood spots) technology
  • Linked to clinical manifestation
  • Quantify easily and reliably in clinical samples
  • Reflect realistically the burden of the disease
  • Elucidate the molecular pathogenesis of the disease
  • Reflect the therapeutic measure outcomes

Novel tandem mass spectrometry (MRM-MS)

  • Proven expertise in the identification of new biomarkers, validated in epidemiological clinical trials
  • Established tandem mass spectrometry (MRM-MS) based biomarker tests for Gaucher, Niemann-Pick type C, Fabry and Farber disease
  • Optimized and facilitated sample logistics with our CE-labeled filtercards, CentoCard®

Application of CENTOGENE’s CE-labeled biomarkers

CentoGaucher, CentoFabry, CentoFarber and CentoNPC are the first CE-labeled test methods for exact measuring of the biomarker in Gaucher, Fabry, Farber disease as well as Niemann-Pick disease type C. They are developed as easy and fast screening techniques for measuring the biomarker levels in affected patients based on tandem mass spectrometry (MRM-MS).


Scientific articles

Selected biomarker level

Lyso-Gb1 levels in Gaucher patients, Gaucher carriers and healthy controls

Lyso-Gb1 is specifically increased in Gaucher patients compared with healthy controls. The affected Gaucher patients can be clearly distinguished from the Gaucher carrier cohort and healthy control cohort.


Get in touch with our Business Development team

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Medical Expert Team Member
Medical Expert Team Member
Medical Expert Team Member
Medical Expert Team Member
Medical Expert Team Member