Whole Exome and Whole Genome Sequencing Course

Who should attend: 

Clinicians, medical doctors, geneticists, genetic counsellors and clinical scientists, who are interested in:

  • Gaining deep insights about Whole Genome Sequencing (WGS) and Whole Exome Sequencing (WES) workflow from sample via lab to report
  • Benefiting from experiences via intensive lectures and hands-on workshops supervised by our experts
  • Taking the unique opportunity to discuss with our experts and exchange with others from the field


  • Basic knowledge of molecular genetics and clinical genetics
  • Basic knowledge of clinical variant databases
  • Basic understanding of data filtering


1. Diagnostic Testing at CENTOGENE

  • Overview of diagnostic tests and quality aspects
  • Products, services and technical background for WES and WGS
  • Company lab tour with extended NGS-laboratory part

2. Bioinformatics

  • Lecture: bioinformatics analysis of WES data as well as WGS data
  • Hands-on analysis of real WES/WGS cases:
    • Alignment, variant calling, and functional annotation of variants by using special bioinformatics pipeline for WES and WGS

3. Medical Evaluation & Reporting

  • Indications for WES and WGS and strategies for analyses, comparison of whole genome vs. whole exome sequencing
  • Hands-on analysis of real WES/WGS cases:
    • Filtering and evaluation of variants using databases
    • Interpretation and implication of clinical information
  • Medical interpretation and reporting, considering clinical information and incidental findings

4. Additional Training

  • CentoPortal®
  • HPO terminology and clinical data interpretation

5. Networking at CENTOGENE

  • Expertise sharing with colleagues from different countries
  • Appointments at Centogene upon request, concerning your individual topics

Price: 1,950 EUR

The workshop fee further includes comprehensive workshop materials, catering during workshop, and a dinner. Computers are provided for data analysis. Free Wi-Fi will be available for tablets, PCs and mobile phones.