Reproductive Health

Identifying genetic causes of infertility facilitates informed decisions and family planning for your patients. With 10% of infertility cases being linked to genetic factors, their detection can provide vital answers. Genetic testing can be the key for a significant number of infertile couples trying to have children, as understanding the reason for infertility can often lead to success with a range of assisted reproductive techniques.

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CentoScreen® Solo

CentoScreen® is our comprehensive screening panel that covers more than 300 common autosomal recessive and X-linked disorders. It provides the opportunity to make informed decisions and review the range of options available to guide pregnancy and family planning. Includes complete panel evaluation with CNV analysis* of 34 genes.

No. of genes: 330
TAT: 25 business days
Coverage: ≥99.00% ≥20x
Details:
NGS including CNV analysis
Sanger sequencing: CYP21A2
Repeat expansion analysis: FMR1
MLPA: SMN1

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CentoScreen® Duo

Includes complete panel evaluation with CNV analysis of 34 genes for each partner.

No. of genes: 330
TAT: 25 business days
Coverage: ≥99.00% ≥20x
Details:
NGS including CNV analysis
MLPA: SMN1
Sanger sequencing: CYP21A2
Repeat expansion analysis: FMR1

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CentoScreen® Paired

Includes complete panel evaluation with CNV analysis of 34 genes + risk gene analysis of partners.

No. of genes: 330
TAT: 30 business days
Coverage: ≥99.00% ≥20x
Details:
NGS including CNV analysis
Repeat expansion analysis: FMR1
Sanger sequencing: CYP21A2
MLPA: SMN1

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COMMON SYNDROMES AND DISORDERS COVERED
  • Alport disease
  • Bardet-Biedl syndromes
  • Congenital adrenal hyperplasia
  • Cystic fibrosis
  • Fragile X syndrome
  • Glycine encephalopathy
  • Maple syrup urine disease
  • Mucolipidosis, several types
  • Mucopolysaccharidosis, several types
  • Niemann-Pick disease
  • Spinal muscular atrophy
  • Organic acidemias
  • Wilson disease

Fertility panel

Our Fertility panel is recommended for couples trying to conceive for one year or longer, who have experienced more than one miscarriage, with irregular or absent menstruation, with low sperm count, form, or movement, or with absence of development of secondary sexual features. Knowing the exact cause of infertility allows for better clinical management and enables enhanced counseling and personalized reproductive care plan for couples. This NGS-only panel option does not include sex chromosome aneuploidy, Y chromosome microdeletions and FMR1-related Premature ovarian failure syndrome testing. For a more comprehensive analysis, please refer to our Fertility X and Fertility Y panels.

No. of genes: 276
TAT: 25 business days
Coverage: ≥99.00% ≥20x
Details:
NGS including CNV analysis

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COMMON SYNDROMES AND DISORDERS COVERED
  • Androgen insensitivity syndrome
  • Hypogonadotropic hypogonadism
  • Monogenic causes of female infertility
  • Monogenic causes of male infertility
  • Ovarian hyperstimulation syndrome
  • Premature ovarian failure (not FMR1-related)
  • Primary ciliary dyskinesia
  • Spermatogenic failure

Fertility X panel

Our Fertility X panel is recommended for patients assigned female gender at birth trying to conceive for one year or longer, who have experienced more than one miscarriage, with irregular or absent menstruation, or with absence of development of secondary sexual features. Our panel includes the most important genes related to infertility in females. Knowing the exact cause of infertility allows for better clinical management and enables enhanced counseling and personalized reproductive care plan for couples. Includes MLPA for aneuploidy.

No. of genes: 276
TAT: 25 business days
Coverage: ≥99.0% ≥20x
Details:
NGS including CNV analysis
Repeat expansion analysis: FMR1

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COMMON SYNDROMES AND DISORDERS COVERED
  • Complete androgen insensitivity syndrome
  • Hypogonadotropic hypogonadism
  • Monogenic causes of female infertility
  • Ovarian hyperstimulation syndrome
  • Premature ovarian failure
  • Turner syndrome

Fertility Y panel

Our Fertility Y panel is recommended for patients assigned male gender at birth with known fertility problems, part of a couple that has experienced more than one miscarriage, with low sperm count, form, or movement, or with absence of development of secondary sexual features. Our panel includes the most important genes related to infertility in males. Knowing the exact cause of infertility allows for better clinical management and enables enhanced counseling and personalized reproductive care plan for couples. Includes MLPA for aneuploidy and the AZF region.

No. of genes: 276
TAT: 25 business days
Coverage: ≥99.0% ≥20x
Details:
NGS including CNV analysis

Order now Sample Requirements

COMMON SYNDROMES AND DISORDERS COVERED
  • CFTR-associated infertility
  • Hypogonadotropic hypogonadism
  • Klinefelter syndrome
  • Monogenic causes of male infertility
  • Primary ciliary dyskinesia
  • Spermatogenic failure
  • Y chromosome microdeletions

Visit Our Online Ordering Portal

CentoPortal® is a user-friendly, online, web-based ordering portal designed to assist you at every step of processing your patients' samples.

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