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  1. Nephrology

Nephrology

CENTOGENE provides genetic testing and consultation for the most efficient diagnosis of inherited kidney-related diseases. Recent advances in genetic techniques provide many important insights into kidney disease diagnosis, classification, pathogenesis, and time-sensitive therapy options. Having identified genetic variants associated with nephrological diseases in more than 300 different genes, we can support you in providing your patients with rapid, effective genetic testing to get a clear understanding of their condition.

Atypical hemolytic uremic syndrome panel

Our atypical hemolytic uremic syndrome panel contains genes for the molecular diagnosis of atypical hemolytic uremic syndrome.

No. of genes:20
TAT:25 days
Coverage:≥99.5% ≥20x
Details:MLPA: CFH, CFHR1, CFHR2, CFHR3, CFHR5

COMMON SYNDROMES AND DISORDERS COVERED

Atypical Hemolytic Uremic syndrome

CentoNephro

Approximately 10% of the population worldwide is affected by chronic kidney diseases. Advances in genetic techniques are providing insights into kidney disease diagnosis, pathogenesis, and therapy. CentoNephro offers a comprehensive tool to screen for most prominent hereditary kidney disorders, including polycystic kidney disease, Alport syndrome, renal tubular acidosis panel, focal glomerulonephrosis panel, and primary hyperoxaluria, among others. PDK1 analysis is not included in this panel.

No. of genes:303
TAT:25 days
Coverage:≥99.5% ≥20x


CentoNephro Plus

If polycystic kidney disease is suspected CentoNephro Plus is recommended, which includes PKD1 analysis.

No. of genes:304
TAT:25 days
Coverage:≥99.5% ≥20x
Details:with CNV and PKD1 analysis

COMMON SYNDROMES AND DISORDERS COVERED

Alport syndrome
Bardet-Biedl syndrome
Bartter syndrome
Combined pituitary hormone deficiency
Focal Segmental glomerulosclerosis
Heterotaxy syndrome
Hypogonadotropic hypogonadism
Intrahepatic cholestasis
Joubert syndrome
Kallmann syndrome
Leber congenital amaurosis
Meckel syndrome
Nephronophthisis
Nephrotic syndrome
Polycystic kidney disease
Pseudohypoaldosteronism
Primary ciliary dyskinesia
Renal tubular acidosis
Skeletal dysplasia
Skeletal ciliopathy

Get in touch with our Partner Support

Our consultation service is available in several languages.

+49 (0) 381 - 80113 416

Mon. – Fri. 7 a.m.– 8 p.m. CET • Sat. 9 a.m. – 5 p.m. CET

For our US Partners:

+1 (617) 580-2102

Mon. – Fri. 9 a.m. – 5:30 p.m. EST