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  1. Immunology

Immunology

Precise diagnosis of immune-related disorders is the basis for establishing life-changing treatment and management options. By leveraging CentoMD®, our robust mutation database for rare diseases, we carefully curate and document all variants that have clinical relevance for related symptoms – providing the most comprehensive diagnosis of immune-related diseases.

Bone marrow failure/anemia panel

Our bone marrow failure/anemia panel is intended for patients with abnormalities in more than 2 blood cell types (red blood cell, white blood cell, and platelets) who present symptoms of lethargy, recurrent infections, excessive bleeding, abnormal pigmentation, enlarged spleen, and malignancies. Some specific disorders detected with this panel are hemophagocytic lymphohistiocytosis, Seckel syndrome, thrombocytopenia, Fanconi anemia, dyskeratosis congenita, Shwachman Diamond syndrome as well as other types of anemias, such as thalassemia alpha and beta, sickle cell disease, spherocytosis, megaloblastic anemia, congenital sideroblastic, and dyserythropoietic anemia.

No. of genes:155
TAT:25 days
Coverage:≥99.5% ≥20x

COMMON SYNDROMES AND DISORDERS COVERED

Bone marrow failure syndrome
Congenital dyserythropoietic anemia
Congenital sideroblastic anemia
Diamond-Blackfan anemia
Fanconi anemia
Hemophagocytic lymphohistiocytosis
Hereditary spherocytosis
Megaloblastic anemia
Seckel syndrome
Thrombocytopenia

CentoImmuno

CentoImmuno is our solution for immunodeficiency and SCID disorders. Our panel includes genes targeting severe combined immunodeficiency, congenital neutropenia, primary antibody deficiency, common variable immune deficiency, chronic granulomatous disease, autoimmune lymphoproliferative, and agammaglobulinemia.

No. of genes:149
TAT:25 days
Coverage:≥99.5% ≥20x

COMMON SYNDROMES AND DISORDERS COVERED

Agammaglobulinemia
Autoimmune lymphoproliferative syndrome
B-cell-negative severe combined immunodeficiency
B-cell-positive severe combined immunodeficiency
Chronic granulomatous disease
Common variable immune deficiency
Congenital afibrinogenemia
Congenital neutropenia syndromes
Hermasky-Pudlak syndrome
Mendelian susceptibility to mycobacterial diseases
Periodic fever syndrome
Primary antibody deficiency
Primary ciliary dyskinesia
Severe combined immunodeficiency

Get in touch with our Partner Support

Our consultation service is available in several languages.

+49 (0) 381 - 80113 416

Mon. – Fri. 7 a.m.– 8 p.m. CET • Sat. 9 a.m. – 5 p.m. CET

For our US Partners:

+1 (617) 580-2102

Mon. – Fri. 9 a.m. – 5:30 p.m. EST