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Genetic Testing for Hereditary Cancers Can Help Reduce the Risk of Cancer

By detecting cancer early, your patient will have access to preventative measures and proactive treatment – leading to an overall better prognosis.

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Genetic Diagnosis of Hereditary Cancer

Testing for hereditary cancers can detect specific, heritable, disease-related gene mutations that may increase the risk of certain cancers allowing an in-depth cancer risk assessment for each patient.

The critical goal is to detect cancer early and to give you the opportunity to maximize health outcomes for your patients. Patient-tailored screening programs, preventive measures and proactive treatment are possible for patients of a high-risk group. Early diagnosis can mean a better overall prognosis through a choice of surgical and non-surgical treatment options.

Hereditary Cancer Feature List

Excellent analysis using the most advanced NGS technology

Includes detection of Copy Number Variants (CNVs)

Affordable prices and shortest turnaround times

Highest level of quality/accuracy

CAP and CLIA and ISO certification and accreditation

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Breast and Ovarian Cancer

Providing critical information for affected and non-affected individuals

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Comprehensive Cancer Panel

CentoCancer® – CENTOGENE's cancer-risk-related panel, for all patients with a positive family history of cancer

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Visit Our Online Ordering Portal

CentoPortal® is a user-friendly, online, web-based ordering portal designed to assist you at every step of processing your patients' samples.

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Breast and Ovarian Cancer

Breast cancer is one of the most common cancers in the world affecting ~12.5% of women during their lifetime. 5–10% of these patients have a hereditary form.

Mutations in the BRCA1 and BRCA2 genes are the most common hereditary cause. However, other genes such as ATM, BRIP1, CHEK2, PALB2, RAD51, etc. have also been associated with increased risk.

Gene test

BRCA1/BRCA2 

CentoBreast®

Gene name BRCA1, BRCA2 ABRAXAS1, ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, DICER1, EPCAM, FANCC, MEN1, MLH1, MRE11, MSH2, MSH6, MUTYH, NBN, PALB2, PMS1, PMS2, PTEN, RAD50, RAD51C, RAD51D, RECQL, SMARCA4, STK11, TP53, XRCC2
Diseases covered Breast cancer Breast cancer, ovarian cancer
Turnaround time 15 business days 15 business days
How to order Order a test Order a test

Comprehensive Cancer Panel

CentoCancer® is a specific and sensitive panel with all known highly penetrant cancer genes. Each gene has been carefully selected based on its risk potential in the development of one of the following cancers: breast, ovarian, colorectal, gastric, bowel, endometrial, pancreatic, melanoma, renal and prostate cancer.

Gene test

CentoCancer®

Genes name ABRAXAS1, APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, DICER1, DIS3L2, EPCAM, FANCC, FH, FLCN, GALNT12, HNF1B, HOXB13, KIT, MC1R, MEN1, MET, MITF, MLH1, MLH3, MRE11, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS1, PMS2, POLD1, POLE, POT1, PRSS1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, RNF43, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, SMARCA4, STK11, TGFBR2, TP53, TSC1, TSC2, VHL, WT1, XRCC2, XRCC3
Diseases covered Breast, ovarian, colorectal, gastric, bowel, endometrial, pancreatic, melanoma, renal and prostate cancer
Turnaround time 15 business days
How to order Order a test
Resources

Downloads

CENTOGENE Hereditary Cancer Productsheet English PDF

Hereditary Cancer Panels – Product Sheet

Genetic testing for an improved prognosis

Scientific Publications

Mechanistic Insights Into Cancer Predisposition

Genetic predisposition to cancer is tightly linked to an increased rate of somatic mutations. For one of the corresponding syndromes, the underlying defect has now been revealed to affect the DNA […]

Article
26 Aug, 2020
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