Where clinical utility meets patient affordability

Get high diagnostic value at a fixed price

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Clinical exome sequencing

Our largest NGS panel available is CentoDx Plus™, covering over 3,200 diseases in the shortest turnaround time. It targets only genes associated with known clinical phenotypes, thereby comprising the complete clinical exome and reducing additional costs.

Who will benefit from CentoDx Plus™?

  • Patients with unknown phenotype where whole exome sequencing is not affordable
  • Patients with identified phenotype in need of a large NGS panel
  • Physicians needing knowledge about clinically relevant genes

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The CentoDx Plus™ advantage


Covers ~6,700 clinically relevant genes with known associated phenotypes

Customizable gene list by giving genes of interest

Sanger confirmation of all reported variants

Turnaround time of <30 business days

Highly affordable, fast and accurate

Why you should choose CentoDx Plus™?

CENTOGENE products Genes Coverage Information content Likelihood of detecting a specific mutation
Clinical exome sequencing - CentoDx Plus™ ~6,700 ~95% >20x ~15MB ~94.1%
Whole exome sequencing - CentoXome® ~20,000 ~97% >10x ~60MB ~93.2%
NGS Panel Genomic ~10-1,000 ~99% >10x 200-500MB ~99.1%

Disorders covered with CentoDx Plus™

  • Metabolic
  • Neurological
  • Reproductive
  • Malformative
  • Ophthalmological
  • Oncogenetic
  • Bone, skin & immunological
  • Cardiovascular
  • Ear, nose & throat
  • Nephrological
  • Hematological
  • Vascular
  • Endocrinal
  • Gastrointestinal
  • Muscoloskeletal

High diagnostic accuracy with the fast workflow