Next Generation Sequencing - our panels
Next Generation Sequencing (NGS) defines an umbrella of new methods for reading nucleotide bases in DNA molecules. NGS was developed to address a need for low-cost high-throughput sequencing technologies in research and diagnostic practices. These methods provide an opportunity for cheap sequencing of millions of DNA molecules in a single run allowing hundreds of genes and entire genomes to be read over a very short period of time.
We are pleased to provide details on how Next Generation Sequencing is performed at Centogene
(see pdf).
Please find below our NGS panels:
Neurological diseases
- ALS - panel
- Cerebellar ataxia, CAP
- CMT neuropathy demyelinating
- CMT neuropathy axonal AD
- Congenital myopathy
- Congenital myasthenic syndrome
- Early infantile epileptic encephalopathy
- Epilepsy childhood absence
- Epilepsy partial familial
- Epilepsy generalized with febrile seizures
- Epileptic encephalopathy early infantile
- Joubert syndrome
- Joubert/Meckel Gruber syndrome
- Leukodystrophy
- Limb-girdle muscular dystrophy
- Mental retardation, X-linked
- Microcephaly Panel
- Mucopolysaccharidosis
- Myofibrillar myopathy
- Myopathy-rhabdomyolysis syndrome
- NEB
- Nemaline myopathy
- Optic atrophy (OA)
- RYR1 (full sequencing)
- Spastic paraplegia (SPG) (AD)
- Spastic paraplegia (SPG) (AR)
- SYNE1
- SYNE2
- Ullrich congenital muscular dystrophy
Metabolic diseases
- Aicardi-Goutieres syndrome
- Ceroid lipofuscinosis
- Fanconi anemia
- Leigh syndrome and mitochondrial encelopathy
- Lyssencephaly
- Urea cycle disorder
- Zellweger syndrome
Cardiological diseases
- Aortic Aneurysm, familial thoracic
- Arrhythmia, familial
- Arrhythmogenic Right Ventricular Cardiomyopathy
- Brugada syndrome
- Cardiomyopathy hypertrophic
- Cardiomyopathy dilated
- Catecholaminergic polymorphic ventricular tachycardia
- Long QT syndrome
- Marfan Syndrome, TAAD and Related Disorders
Ophthalmological diseases
- Albinism
- Cataract panel AR
- Cone rod and cone dystrophy CORD AD
- Cone-rod and cone dystrophy CORD AR
- Hermansky-Pudlak syndrome
- Leber congenital amaurosis
- Oculomotor apraxia
- Progressive external ophthalmoplegia (PEO)
- Retinitis pigmentosa (AD)
- Retinitis pigmentosa (AR)
