Genetic insights Ophthalmology
There are more than 1,800 syndromes that involve eye disease as a component, and further individual and family case reports of hereditary eye disorders not yet classified. More than 60 % of cases of blindness among infants are caused by inherited eye diseases such as congenital (present at birth) cataracts,
congenital glaucoma, retinal degeneration, optic atrophy and eye malformations.
Genetics play a significant role in ophthalmological problems. There is evidence that most common problems related to the eyes among children and adults are genetically determined. The list includes strabismus (cross-eyes), ambylopia (lazy eye) and refraction errors such as myopia (nearsightedness), hyperopia (farsightedness) and astigmatism. Eye abnormalities are present in one-third of inherited, systemic diseases. The presence of a particular ocular sign known to be associated with a systemic disease often is the deciding factor in confirming the diagnosis of that disease.
CENTOGENE‘s work does not end with the identification of the genetic mutation behind a particular disorder. Our self-conception leads to comprehensive interpretation of medical results and case-to-case consultation whenever it is needed.
Prof. Arndt Rolfs, MD Chief Executive Officer